Gatlinburg, TN entrance
From interstate highway I-40 take Exit 407 (Sevierville) to TN-66 South. At the Sevierville intersection, continue straight onto US-441 South. Follow US-441 through Sevierville and Pigeon Forge into park.

Townsend, TN entrance
From the north: From interstate highway I-40 in Knoxville take Exit 386B to US-129 South to Alcoa/Maryville. At Maryville proceed on US-321 North/TN -73 East through Townsend. Continue straight on TN-73 into the park.

From the south: From interstate highway I-75 take Exit 376 to I-140 E towards Oak Ridge/Maryville. Merge onto I-140 E via Exit 376B towards Maryville. Turn onto US-129 South (Alcoa Highway) at Exit 11A and travel towards Alcoa. Turn onto TN-35 and follow it to US-321 North. Follow US-321 North/TN -73 East through Townsend. Continue straight on TN-73 into the park.


Cherokee, NC entrance
From the north: From interstate highway I-40, take Exit 27 to US-74 West towards Waynesville. Turn onto US-19 and proceed through Maggie Valley to Cherokee. Turn onto US-441 North at Cherokee and follow the road into the park.

From the south: Follow US-441/US-23 North. At Dillsboro merge on US-74 West/US-441 North. At Exit 74 merge onto US-441. Follow US-441 through Cherokee and into the park.