Interstate 44 East/55 North: Take Exit 292 for Lumiere Place Blvd./Washington Ave./Eads Bridge then take the u-turn from the left lane to access Pine Street and downtown.

Interstate 64 East: Take Exit 40 for Last Missouri Exit. Turn left onto Gratiot, then left onto Fourth Street. Continue north on Fourth Street to access downtown.

Interstate 70 East: Take Exit 249B for Tucker Blvd. Turn left onto Market Street to access downtown.

Exiting from Illinois Interstates 55, 64, &70 via Poplar Street Bridge, Martin Luther King Bridge, Eads Bridge, and Stan Musial Veterans Memorial Bridge

Poplar Street Bridge: (55 South/64 West): After crossing the bridge, continue on 64/40 West and take Exit 40A for Stadium/Tucker Blvd. Continue straight off the exit then turn right on Walnut Street to access downtown.

Martin Luther King Bridge: After crossing the bridge, turn left under the interstate onto Carr Street followed by an immediate left onto Broadway to access downtown.

Eads Bridge: After crossing the bridge, continue straight on Washington Avenue to access downtown.

Stan Musial Veterans Memorial Bridge: After crossing the bridge, take the left exit for North Tucker Blvd. Turn left on Market Street to access downtown.